Prostate cancer is the most common cancer among men in many countries, including the US and UK. About 1.5 million men are diagnosed worldwide each year.
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A difficulty here, however, is that the TransformStreamDefaultController does not have a ready promise mechanism like Writers do; so the TransformStream implementation would need to implement a polling mechanism to periodically check when controller.desiredSize becomes positive again.
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Every fragment means promises created for read() calls, promises for backpressure coordination, intermediate buffer allocations, and { value, done } result objects — most of which become garbage almost immediately.